The Tytgat Institute for Liver and Intestinal Research, Amsterdam University UMC is looking for a postdoctoral researcher with high potential to eventually complement their staff as a group leader.
The liver is the first organ to detect and integrate the signals from gut-derived metabolites and plays a dominant role in controlling their spatial and temporal signaling. The ultimate goal of this research project is to exploit intestinal-derived signals by modulating hepatic metabolite uptake and/or catabolism to prevent or target common metabolic diseases, such as type 2 diabetes, NAFLD, and atherosclerosis.
Also, the overall aim of this research area is the development of novel treatment strategies for inherited liver disorders. Historically, the department is very strong in the development of viral vector-based gene therapy. They will be moving towards gene repair and gene editing using lipid nanoparticle (LNP) vectors to deliver Cas RNA or protein guide RNAs. Furthermore, they will explore the translation of technological advancements in (temporal) gene modification also to other applications beyond rare inherited disorders.
Duration: The position is for 3 years
Salary
- a competitive gross monthly salary of € 3.047 – € 4.800.
- In addition to a good basic salary, they offer an 8.3% end-of-year bonus and an 8% holiday allowance.
- Pension accrual with Befrank, a modern, transparent, and understandable pension plan.
- Reimbursement of 75% of their public transport costs
- The unique opportunity to work in a multidisciplinary international translational research team.
- Access to, and training in, state-of-the-art technologies in biomedical research.
- A dynamic working environment in which quality, professionalism, and team spirit are encouraged (with English as the main language).
- Training in project management (e.g., supervision of students, budget management).
Job Requirements
They are looking for a highly driven, motivated, and enthusiastic researcher with:
- A PhD in a field related to biomedical molecular sciences.
- Interest in innovative technologies and pushing the boundaries of research through technology-driven applications;
- Experience with in vitro and in vivo models. Experience with advanced ex vivo models (precision cut liver slices, organoids, perfusion systems) is a strong advantage.
- A flexible, pro-active team spirit but you can also work independently;
- Excellent communication skills in English, both written and verbal.
- A strong collaboration network.
- A strong publication record in prestigious international journals.
Application Process
To apply as a Postdoc/Junior Group Leader Liver Research, click here.
Application Deadline: October 09, 2022.
For more information, visit the official site.
